Basic Information
ID: ALA5036693
Type: Binding
Description: Inhibition of human recombinant HAO1 assessed as detecting hydrogen peroxide using glycolic acid as substrate preincubated for 30 min followed by substrate addition measured after 15 mins by microplate reader
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5036693
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.74 | 3.04 | 3.04 |
| 297.31 | 2.89 | 2.89 |
| 392.48 | 4.64 | 4.64 |
| 378.39 | 2.99 | 2.99 |
| 350.38 | 3.00 | 3.00 |
| 340.38 | 3.08 | 3.08 |
| 393.40 | 3.75 | 3.75 |
| 380.43 | 4.01 | 4.01 |
| 406.51 | 5.14 | 5.14 |
| 344.16 | 2.43 | 2.43 |
| 395.38 | 2.66 | 2.66 |
| 422.51 | 4.85 | 4.85 |
| 392.42 | 4.36 | 4.36 |
| 436.47 | 3.50 | 3.50 |
| 412.84 | 3.64 | 3.64 |
| 394.39 | 2.69 | 2.69 |
| 394.46 | 4.32 | 4.32 |
| 378.46 | 4.33 | 4.33 |
| 408.48 | 4.83 | 4.83 |
| 391.43 | 4.02 | 4.02 |
| 352.36 | 1.79 | 1.79 |
| 408.42 | 2.72 | 2.72 |
| 408.42 | 2.71 | 2.71 |
| 191.19 | 1.30 | 1.30 |
| 354.37 | 2.28 | 2.28 |
| 471.32 | 6.25 | 6.25 |
| 422.45 | 3.11 | 3.11 |
| 408.42 | 2.78 | 2.78 |
| 393.41 | 2.10 | 2.10 |
| 267.29 | 2.87 | 2.87 |
| 248.29 | 1.23 | 1.23 |
| 393.40 | 3.30 | 3.30 |
| 408.42 | 3.00 | 3.00 |