Basic Information
ID: ALA5038472
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated human THP-1 cells assessed as blockade of pro caspase 1 p20 in LPS stimulation followed by pretreatment for 40 min before induced with nigericin for 40 min measured by western blot analysis
Format: BAO_0000221
Organism: Homo sapiens
Cell type: THP-1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA1741208)
Document: ALA5036380
Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated human THP-1 cells assessed as blockade of pro caspase 1 p20 in LPS stimulation followed by pretreatment for 40 min before induced with nigericin for 40 min measured by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5038472
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.20 | 4.50 | 4.50 |