Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated human THP-1 cells assessed as reduction in pyroptosis in LPS stimulation for 3 hr...

Basic Information

ID: ALA5038474

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated human THP-1 cells assessed as reduction in pyroptosis in LPS stimulation for 3 hrs followed by pretreatment for 40 min before induced with nigericin for 40 min by propidium iodide staining based inverted microscopic assay

Format: BAO_0000221

Organism: Homo sapiens

Cell type: THP-1

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA5036380

Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated human THP-1 cells assessed as reduction in pyroptosis in LPS stimulation for 3 hrs followed by pretreatment for 40 min before induced with nigericin for 40 min by propidium iodide staining based inverted microscopic assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
365.204.504.50