Binding affinity to NLRP3 in LPS stimulated human THP-1cells assessed as prevention of pronase-mediated protein degradation at 0.01 to 1mM incubated 5...

Basic Information

ID: ALA5038486

Type: Binding

Description: Binding affinity to NLRP3 in LPS stimulated human THP-1cells assessed as prevention of pronase-mediated protein degradation at 0.01 to 1mM incubated 50 mins before pronase treatment by label-free DARTS assay

Format: BAO_0000221

Organism: Homo sapiens

Cell type: THP-1

Target:  NACHT, LRR and PYD domains-containing protein 3(ALA1741208)

Document:  ALA5036380

Binding affinity to NLRP3 in LPS stimulated human THP-1cells assessed as prevention of pronase-mediated protein degradation at 0.01 to 1mM incubated 50 mins before pronase treatment by label-free DARTS assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
365.204.504.50