Basic Information
ID: ALA5038526
Type: Binding
Description: Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA5038526
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.42 | 2.29 | 2.29 |
| 400.48 | 3.22 | 3.22 |
| 386.46 | 2.83 | 2.83 |
| 402.45 | 2.06 | 2.06 |
| 346.39 | 1.95 | 1.95 |
| 333.35 | 1.72 | 1.72 |
| 332.36 | 1.69 | 1.69 |
| 388.47 | 3.07 | 3.07 |
| 344.37 | 1.70 | 1.70 |
| 380.40 | 1.40 | 1.40 |
| 394.43 | 1.44 | 1.44 |
| 418.47 | 3.16 | 3.16 |
| 436.46 | 3.46 | 3.46 |
| 404.45 | 2.77 | 2.77 |
| 400.48 | 3.26 | 3.26 |
| 414.51 | 3.61 | 3.61 |
| 396.45 | 1.69 | 1.69 |
| 374.44 | 2.68 | 2.68 |
| 425.49 | 2.97 | 2.97 |
| 404.45 | 2.77 | 2.77 |
| 388.43 | 1.62 | 1.62 |
| 364.45 | 2.29 | 2.29 |
| 428.54 | 3.99 | 3.99 |
| 436.46 | 3.46 | 3.46 |
| 386.46 | 2.82 | 2.82 |
| 386.46 | 2.83 | 2.83 |
| 418.52 | 2.78 | 2.78 |
| 386.46 | 2.87 | 2.87 |
| 422.44 | 3.07 | 3.07 |
| 402.45 | 2.53 | 2.53 |
| 432.48 | 1.51 | 1.51 |
| 359.43 | 2.86 | 2.86 |
| 404.45 | 2.77 | 2.77 |
| 415.50 | 1.98 | 1.98 |
| 418.47 | 3.16 | 3.16 |
| 400.48 | 3.22 | 3.22 |
| 360.42 | 2.29 | 2.29 |
| 386.46 | 2.82 | 2.82 |
| 386.46 | 2.83 | 2.83 |
| 358.45 | 3.47 | 3.47 |
| 400.48 | 3.22 | 3.22 |
| 450.52 | 1.46 | 1.46 |
| 372.43 | 2.48 | 2.48 |
| 416.38 | 1.99 | 1.99 |
| 390.49 | 2.55 | 2.55 |
| 416.48 | 2.23 | 2.23 |