Basic Information
ID: ALA5039004
Type: Binding
Description: PROTAC activity at CRBN E3 ligase/EZH2 in PRC2 complex in human WSUDLCL2 cells assessed as induction of SUZ12 degradation at 1 uM incubated for 48 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: WSUDLCL2
Activity Charts
Bioactivity
Activity Types for Assay ALA5039004
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.69 | 4.63 | 4.63 |
| 572.75 | 4.73 | 4.73 |
| 939.17 | 7.94 | 7.94 |
| 970.22 | 7.23 | 7.23 |
| 897.09 | 6.77 | 6.77 |
| 984.25 | 7.62 | 7.62 |
| 869.04 | 5.99 | 5.99 |
| 956.20 | 6.84 | 6.84 |
| 1012.31 | ||
| 998.28 | 8.01 | 8.01 |
| 925.14 | 7.55 | 7.55 |
| 914.12 | 5.67 | 5.67 |
| 967.22 | 8.72 | 8.72 |
| 911.12 | 7.16 | 7.16 |
| 900.09 | 5.28 | 5.28 |
| 855.01 | 5.60 | 5.60 |
| 942.17 | 6.45 | 6.45 |
| 953.20 | 8.33 | 8.33 |
| 928.14 | 6.06 | 6.06 |
| 883.06 | 6.38 | 6.38 |