Basic Information
ID: ALA5039134
Type: Binding
Description: PROTAC activity at CRBN E3 ligase/EZH2 in PRC2 complex in human WSUDLCL2 cells assessed as downregulation of EED expression at 1 uM pretreated with lenalidomide for 4 hrs followed by compound addition and measured after 48 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: WSUDLCL2
Activity Charts
Bioactivity
Activity Types for Assay ALA5039134
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 942.17 | 6.45 | 6.45 |