Basic Information
ID: ALA5039193
Type: Functional
Description: Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: G-protein coupled receptor 6(ALA3714130)
Document: ALA5038577
Inverse agonist activity at human GPR6 expressed in CHO-K1 cells assessed as modulation of cAMP level incubated for 20 hrs by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5039193
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.44 | 2.22 | 2.22 |
| 458.39 | 4.84 | 4.84 |
| 429.36 | 4.23 | 4.23 |
| 412.90 | 3.71 | 3.71 |
| 373.50 | 3.83 | 3.83 |
| 428.37 | 4.83 | 4.83 |
| 429.36 | 4.23 | 4.23 |
| 396.45 | 3.20 | 3.20 |
| 396.45 | 3.20 | 3.20 |
| 410.47 | 3.51 | 3.51 |
| 413.47 | 4.48 | 4.48 |
| 412.49 | 3.75 | 3.75 |
| 473.52 | 2.91 | 2.91 |
| 411.46 | 4.23 | 4.23 |
| 413.47 | 4.48 | 4.48 |
| 415.49 | 4.04 | 4.04 |
| 442.39 | 5.14 | 5.14 |
| 441.48 | 3.71 | 3.71 |
| 443.50 | 3.96 | 3.96 |
| 478.57 | 2.64 | 2.64 |
| 441.48 | 3.71 | 3.71 |
| 499.45 | 4.53 | 4.53 |
| 459.50 | 4.18 | 4.18 |
| 442.51 | 3.23 | 3.23 |
| 424.46 | 4.04 | 4.04 |
| 446.36 | 4.97 | 4.97 |
| 456.54 | 3.62 | 3.62 |
| 398.46 | 3.45 | 3.45 |
| 479.55 | 3.37 | 3.37 |
| 401.46 | 3.70 | 3.70 |
| 411.46 | 4.23 | 4.23 |
| 443.50 | 3.96 | 3.96 |
| 453.38 | 4.70 | 4.70 |