Basic Information
ID: ALA5039568
Type: Binding
Description: Inhibition of recombinant human HDAC8 using Boc-Lys (trifluoroacetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by micro plate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5039568
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 227.26 | 2.32 | 2.32 |
| 296.33 | 2.82 | 2.82 |
| 422.44 | 4.32 | 4.32 |
| 452.92 | 5.14 | 5.14 |
| 419.46 | 3.88 | 3.88 |
| 562.24 | 5.71 | 5.71 |
| 505.58 | 5.19 | 5.19 |
| 506.89 | 5.85 | 5.85 |
| 438.89 | 4.83 | 4.83 |
| 475.55 | 5.10 | 5.10 |
| 434.47 | 4.19 | 4.19 |
| 405.44 | 3.58 | 3.58 |
| 461.52 | 4.79 | 4.79 |
| 501.33 | 5.08 | 5.08 |
| 449.44 | 4.09 | 4.09 |
| 449.44 | 4.09 | 4.09 |
| 519.32 | 5.22 | 5.22 |
| 472.44 | 5.20 | 5.20 |
| 497.37 | 5.25 | 5.25 |
| 404.45 | 4.18 | 4.18 |
| 418.47 | 4.49 | 4.49 |
| 396.45 | 3.37 | 3.37 |
| 434.47 | 4.19 | 4.19 |
| 473.34 | 5.49 | 5.49 |
| 483.34 | 4.94 | 4.94 |
| 496.54 | 5.97 | 5.97 |
| 409.42 | 3.48 | 3.48 |
| 440.43 | 4.46 | 4.46 |
| 423.43 | 3.72 | 3.72 |