Basic Information
ID: ALA5039649
Type: Binding
Description: Inhibition of recombinant TOP1 (unknown origin) at 1 uM using 3'-[32P]-labeled 117 bp DNA oligonucleotides as substrate incubated for 20 mins by PAGE analysis relative to CPT
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5039649
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 420.47 | 3.62 | 3.62 |
| 420.47 | 3.62 | 3.62 |
| 428.41 | 4.62 | 4.62 |
| 392.41 | 3.01 | 3.01 |
| 376.46 | 3.89 | 3.89 |
| 346.43 | 3.88 | 3.88 |
| 439.31 | 4.36 | 4.36 |
| 405.41 | 3.51 | 3.51 |
| 436.51 | 3.90 | 3.90 |
| 406.44 | 3.31 | 3.31 |
| 346.43 | 3.88 | 3.88 |
| 360.41 | 3.60 | 3.60 |
| 360.41 | 3.60 | 3.60 |
| 316.40 | 3.87 | 3.87 |
| 404.42 | 3.33 | 3.33 |
| 408.45 | 3.30 | 3.30 |
| 422.48 | 3.60 | 3.60 |
| 390.44 | 3.61 | 3.61 |
| 376.46 | 3.89 | 3.89 |
| 448.52 | 4.39 | 4.39 |
| 390.44 | 3.61 | 3.61 |
| 346.43 | 3.88 | 3.88 |
| 422.48 | 3.60 | 3.60 |
| 378.40 | 3.74 | 3.74 |
| 378.40 | 3.74 | 3.74 |
| 436.51 | 3.90 | 3.90 |
| 346.43 | 3.88 | 3.88 |
| 420.47 | 3.62 | 3.62 |
| 406.44 | 3.31 | 3.31 |
| 346.43 | 3.88 | 3.88 |
| 395.30 | 4.63 | 4.63 |
| 436.51 | 3.90 | 3.90 |
| 406.44 | 3.31 | 3.31 |
| 420.47 | 3.62 | 3.62 |
| 420.47 | 3.62 | 3.62 |
| 392.41 | 3.01 | 3.01 |
| 394.86 | 4.25 | 4.25 |
| 346.43 | 3.88 | 3.88 |
| 390.44 | 3.61 | 3.61 |
| 346.43 | 3.88 | 3.88 |
| 448.52 | 4.39 | 4.39 |
| 360.41 | 3.60 | 3.60 |
| 346.43 | 3.88 | 3.88 |
| 352.38 | 4.15 | 4.15 |
| 346.43 | 3.88 | 3.88 |
| 346.43 | 3.88 | 3.88 |
| 332.40 | 3.58 | 3.58 |
| 406.44 | 3.31 | 3.31 |
| 396.39 | 3.88 | 3.88 |
| 376.46 | 3.89 | 3.89 |
| 404.42 | 3.33 | 3.33 |
| 376.46 | 3.89 | 3.89 |