Assay Report Card

Basic Information

ID: ALA5039973

Type: Binding

Description: Protac activity at CRBN/EGFR in human SW1990 cells assessed as decrease in EGFR expression level at 1 to 50 uM pretreated with proteasome inhibitor MG132 for 4 hr followed by incubation with compound for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: SW1990

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1313.73