Basic Information
ID: ALA5039974
Type: Binding
Description: Protac activity at CRBN/PARP-1 in human SW1990 cells assessed as decrease of PARP-1 expression level at 1 to 50 uM pretreated with proteasome inhibitor MG132 for 4 hr followed by incubation with compound for 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SW1990
Activity Charts
Bioactivity
Activity Types for Assay ALA5039974
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1313.73 |