Basic Information
ID: ALA5039982
Type: Binding
Description: Protac activity at VHL/EGFR in human NCI-H1299 cells assessed as decrease in EGFR degradation at up to 15 uM pretreated with proteasome inhibitor MG132 for 4 hr followed by incubation with compound for 6 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: NCI-H1299
Activity Charts
Bioactivity
Activity Types for Assay ALA5039982
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1562.21 |