Basic Information
ID: ALA5040022
Type: Binding
Description: Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced activation of cGAS incubated for 1 hr by Quanti-luc reagent based assay
Organism: Mus musculus
Cell type: RAW-Lucia ISG
Activity Charts
Bioactivity
Activity Types for Assay ALA5040022
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 415.24 | 4.33 | 4.33 |
| 416.31 | 3.78 | 3.78 |
| 414.29 | 4.07 | 4.07 |
| 515.24 | 5.86 | 5.86 |
| 420.30 | 3.62 | 3.62 |
| 526.26 | 5.65 | 5.65 |
| 378.26 | 2.72 | 2.72 |
| 435.32 | 1.83 | 1.83 |
| 452.73 | 3.61 | 3.61 |
| 379.25 | 2.75 | 2.75 |
| 618.40 | 5.26 | 5.26 |
| 511.36 | 2.87 | 2.87 |
| 458.35 | 4.35 | 4.35 |
| 528.31 | 5.01 | 5.01 |
| 456.33 | 4.64 | 4.64 |
| 448.74 | 4.72 | 4.72 |
| 450.32 | 3.18 | 3.18 |
| 568.30 | 6.22 | 6.22 |
| 486.36 | 3.71 | 3.71 |
| 494.76 | 4.65 | 4.65 |
| 501.37 | 3.42 | 3.42 |
| 392.29 | 2.98 | 2.98 |
| 458.27 | 4.63 | 4.63 |
| 562.40 | 4.86 | 4.86 |
| 494.76 | 4.65 | 4.65 |