Basic Information
ID: ALA5040023
Type: Binding
Description: Inhibition of STING-dependent cGAS activation in cGAMP treated human THP-1-Dual cells assessed as suppression of lipofectamine 2000:cGAMP-induced IRF luciferase expression at 10 uM incubated for 1 hr by Quanti-luc reagent based assay
Organism: Homo sapiens
Cell type: H69AR
Activity Charts
Bioactivity
Activity Types for Assay ALA5040023
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.31 | 3.78 | 3.78 |
| 414.29 | 4.07 | 4.07 |
| 526.26 | 5.65 | 5.65 |
| 378.26 | 2.72 | 2.72 |
| 435.32 | 1.83 | 1.83 |
| 528.31 | 5.01 | 5.01 |
| 458.27 | 4.63 | 4.63 |
| 494.76 | 4.65 | 4.65 |