Basic Information
ID: ALA5040026
Type: Binding
Description: Inhibition of ds-DNA induced cGAS-STING signalling activation in human THP-1-Dual cells assessed as suppression of IRF3 phosphorylation at Ser386 residue at 0.4 to 10 uM incubated for 1 hr followed by transfection with ds-DNA and measured after 2 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: H69AR
Activity Charts
Bioactivity
Activity Types for Assay ALA5040026
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.31 | 3.78 | 3.78 |
| 435.32 | 1.83 | 1.83 |