Basic Information
ID: ALA5040043
Type: Binding
Description: Inhibition of NKCC1 (unknown origin) transfected in HEK293 cells expressing mbYFPQS plasmid assessed as reduction in Cl- influx at 100 uM incubated for 30 mins by fluorescence multiplate reader analysis relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5040043
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.42 | 3.04 | 3.04 |
| 301.37 | 2.23 | 2.23 |
| 286.35 | 1.50 | 1.50 |
| 287.34 | 1.71 | 1.71 |
| 300.38 | 1.85 | 1.85 |
| 410.46 | 3.95 | 3.95 |
| 354.35 | 2.39 | 2.39 |
| 329.42 | 2.84 | 2.84 |
| 382.40 | 3.17 | 3.17 |
| 330.41 | 1.47 | 1.47 |
| 329.42 | 3.01 | 3.01 |
| 273.31 | 1.45 | 1.45 |
| 314.41 | 2.14 | 2.14 |
| 328.43 | 2.80 | 2.80 |
| 315.40 | 2.35 | 2.35 |
| 342.46 | 3.07 | 3.07 |
| 300.38 | 1.88 | 1.88 |
| 356.49 | 3.41 | 3.41 |
| 302.35 | 0.69 | 0.69 |
| 300.38 | 2.02 | 2.02 |
| 272.33 | 1.24 | 1.24 |
| 301.37 | 2.06 | 2.06 |
| 315.40 | 2.50 | 2.50 |
| 329.42 | 2.69 | 2.69 |
| 328.43 | 2.63 | 2.63 |
| 301.37 | 2.09 | 2.09 |