Basic Information
ID: ALA5040107
Type: Binding
Description: Inhibition of recombinant human GST tagged truncated LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate in presence of ATP preincubated for 50 mins followed by anti-phospho-LRRKtide antibody addition and measured after 30 mins by TR-FRET based Lanthascreen kinase activity assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Leucine-rich repeat serine/threonine-protein kinase 2(ALA1075104)
Document: ALA5038598
Inhibition of recombinant human GST tagged truncated LRRK2 G2019S mutant using fluorescein-labeled LRRKtide as substrate in presence of ATP preincubated for 50 mins followed by anti-phospho-LRRKtide antibody addition and measured after 30 mins by TR-FRET based Lanthascreen kinase activity assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5040107
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 135.13 | -0.11 | -0.11 |
| 135.13 | -0.06 | -0.06 |
| 163.18 | 0.42 | 0.42 |
| 364.46 | 2.80 | 2.80 |
| 350.43 | 2.49 | 2.49 |
| 351.42 | 2.19 | 2.19 |
| 419.42 | 2.91 | 2.91 |
| 407.48 | 2.23 | 2.23 |
| 351.42 | 1.89 | 1.89 |
| 407.48 | 2.23 | 2.23 |
| 242.29 | 1.40 | 1.40 |
| 274.33 | 0.64 | 0.64 |
| 385.86 | 2.54 | 2.54 |
| 256.31 | 1.41 | 1.41 |
| 365.45 | 2.20 | 2.20 |
| 242.29 | 1.02 | 1.02 |
| 437.51 | 1.42 | 1.42 |
| 256.31 | 1.41 | 1.41 |
| 421.51 | 2.62 | 2.62 |
| 423.53 | 2.43 | 2.43 |
| 421.51 | 2.62 | 2.62 |
| 365.45 | 2.20 | 2.20 |
| 188.19 | 0.00 | 0.00 |
| 271.33 | 0.99 | 0.99 |
| 255.32 | 2.02 | 2.02 |
| 231.30 | 1.54 | 1.54 |
| 216.25 | 0.49 | 0.49 |
| 423.53 | 2.43 | 2.43 |
| 337.39 | 1.88 | 1.88 |
| 421.51 | 2.62 | 2.62 |
| 278.32 | 2.03 | 2.03 |
| 249.28 | 2.09 | 2.09 |
| 296.31 | 2.17 | 2.17 |
| 285.26 | 2.37 | 2.37 |
| 437.51 | 1.42 | 1.42 |