Basic Information
ID: ALA5040391
Type: ADME
Description: Microsomal stability in human liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA5038608
Microsomal stability in human liver microsomes assessed as intrinsic clearance at 1 uM preincubated for 5 mins followed by NADPH regenerating system addition measured after 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5040391
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 339.39 | 2.30 | 2.30 |
| 471.40 | 3.84 | 3.84 |
| 381.27 | 1.92 | 1.92 |
| 388.27 | 3.37 | 3.37 |
| 468.36 | 4.18 | 4.18 |
| 374.24 | 3.38 | 3.38 |
| 338.41 | 2.64 | 2.64 |
| 392.26 | 2.42 | 2.42 |
| 440.30 | 3.56 | 3.56 |
| 453.34 | 2.79 | 2.79 |
| 324.38 | 2.25 | 2.25 |
| 406.28 | 3.15 | 3.15 |
| 395.30 | 2.17 | 2.17 |
| 327.39 | 1.41 | 1.41 |
| 349.34 | 1.30 | 1.30 |
| 485.43 | 4.08 | 4.08 |
| 392.23 | 3.52 | 3.52 |
| 457.37 | 3.45 | 3.45 |
| 481.39 | 3.57 | 3.57 |
| 481.39 | 3.57 | 3.57 |
| 441.29 | 2.96 | 2.96 |
| 338.34 | 2.62 | 2.62 |
| 495.42 | 3.82 | 3.82 |
| 459.35 | 2.63 | 2.63 |