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Inhibition of CYP2C19 in human liver microsomes using (s)-Mephenytoin as substrate by LC-MS/MS analysis

Basic Information

ID: ALA5040794

Type: ADME

Description: Inhibition of CYP2C19 in human liver microsomes using (s)-Mephenytoin as substrate by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2C19(ALA3622)

Document:  ALA5038620

Inhibition of CYP2C19 in human liver microsomes using (s)-Mephenytoin as substrate by LC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5040794

IC50

Total(1)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
450.582.622.62
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