Assay Report Card

Basic Information

ID: ALA5041256

Type: Binding

Description: Inhibition of HIF-1alpha in mouse C2C12 cells transfected with HRE-driven firefly luciferase gene assessed as fold change in transcriptional activity at 300 uM pretreated with compound for 12 hr followed by hypoxic condition for 24 hrs by dual luciferase reporter gene assay

Organism: Mus musculus

Cell type: C2C12

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
376.410.460.46
284.31-0.95-0.95
362.380.540.54
376.410.460.46
314.33-0.86-0.86
362.380.540.54
376.410.460.46
328.36-0.51-0.51
378.38-0.13-0.13
302.30-0.82-0.82
314.33-0.95-0.95
340.37-0.37-0.37