Assay Report Card

Basic Information

ID: ALA5041727

Type: ADME

Description: Ratio of apparent permeability across apical to basolateral side in the presence of P-gp inhibitor elacridar to the absence of P-gp inhibitor elacridar in dog MDCK-MDR1 cells at 5 uM incubated for 120 mins

Organism: Canis lupus familiaris

Cell type: MDCK

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
414.402.052.05
371.402.042.04
389.392.182.18
420.411.581.58
414.402.052.05