Basic Information
ID: ALA5042826
Type: Functional
Description: Antitumor activity against human RS4-11 cells xenografted in BALB/c nu/nu mouse assessed as reduction in DYRK1A autophosphorylation of S520 residue at 6.25 mg/kg, po measured after 2 hrs by western blotting analysis relative to control
Organism: Mus musculus
Cell type: RS4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA5042826
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 280.34 | 2.30 | 2.30 |
| 322.29 | 2.53 | 2.53 |
| 360.42 | 3.05 | 3.05 |