Assay Report Card

Basic Information

ID: ALA5042827

Type: Functional

Description: Antitumor activity against human RS4-11 cells xenografted in BALB/c nu/nu mouse reduction in DYRK1A autophosphorylation of S520 residue at 6.25 mg/kg, po measured after 6 hrs by western blotting analysis relative to control

Organism: Mus musculus

Cell type: RS4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
280.342.302.30
322.292.532.53
360.423.053.05