Basic Information
ID: ALA5042918
Type: Binding
Description: Inhibition of human factor 12a using H-D-Pro-Phe-Arg-p-nitroanilide as chromogenic substrate assessed as liberation of p-nitroaniline measured every 5 mins for 60 min by multimode plate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5042918
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1956.41 | ||
| 1506.76 | ||
| 1524.75 | ||
| 1480.72 | ||
| 1520.79 | ||
| 1524.75 | ||
| 1531.77 | ||
| 1303.51 | ||
| 1345.59 | ||
| 1556.82 | ||
| 1464.72 | ||
| 1507.75 | ||
| 1508.75 | ||
| 1421.65 | ||
| 1558.76 | ||
| 1388.62 | ||
| 1442.72 | ||
| 1504.79 | ||
| 1358.59 | ||
| 1478.75 | ||
| 1512.81 | ||
| 1492.74 | ||
| 1449.67 | ||
| 1421.65 | ||
| 1536.79 | ||
| 1520.79 | ||
| 896.09 | -2.11 | -2.11 |
| 1491.75 | ||
| 1574.76 | ||
| 954.16 | -1.46 | -1.46 |
| 1508.75 | ||
| 1362.58 | ||
| 1366.66 | ||
| 1574.76 | ||
| 1346.54 | ||
| 1520.79 | ||
| 1464.68 | ||
| 1558.76 | ||
| 1531.77 | ||
| 1331.52 | ||
| 1524.75 | ||
| 1518.77 | ||
| 1402.65 | ||
| 1402.65 | ||
| 1520.79 | ||
| 1536.79 | ||
| 1520.79 | ||
| 1515.77 | ||
| 1421.65 | ||
| 1524.75 | ||
| 1574.76 | ||
| 1520.79 | ||
| 1496.81 | ||
| 1464.72 | ||
| 1491.75 | ||
| 1520.79 | ||
| 1556.82 | ||
| 1296.52 | ||
| 1520.79 | ||
| 1492.73 | ||
| 1515.77 | ||
| 1478.75 | ||
| 1520.79 | ||
| 1491.75 | ||
| 1507.75 | ||
| 1761.04 | ||
| 1520.79 | ||
| 1331.57 | ||
| 1507.75 | ||
| 1520.79 | ||
| 1522.76 | ||
| 1531.77 | ||
| 1490.76 | ||
| 1430.66 | ||
| 1515.77 | ||
| 1551.76 | ||
| 1635.92 | ||
| 1414.66 | ||
| 1536.79 | ||
| 1346.54 | ||
| 1432.72 | ||
| 1536.79 | ||
| 1558.76 | ||
| 1520.79 | ||
| 1462.75 | ||
| 1508.75 | ||
| 1845.12 |