Basic Information
ID: ALA5043455
Type: Binding
Description: Inhibition of STK4 in HEK293 cells assessed as reduction in phosphorylated-MOB1 protein level at 10 uM preincubated for 4 hrs followed by H2O2 addition and measured after 2 hrs by Western blotting analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Serine/threonine-protein kinase MST1(ALA4598)
Document: ALA5042489
Inhibition of STK4 in HEK293 cells assessed as reduction in phosphorylated-MOB1 protein level at 10 uM preincubated for 4 hrs followed by H2O2 addition and measured after 2 hrs by Western blotting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5043455
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.78 | 3.11 | 3.11 |
| 323.36 | 1.56 | 1.56 |
| 298.32 | 2.60 | 2.60 |
| 416.49 | 2.29 | 2.29 |
| 341.85 | 3.47 | 3.47 |
| 302.76 | 2.71 | 2.71 |
| 312.80 | 4.27 | 4.27 |
| 294.36 | 2.77 | 2.77 |
| 328.80 | 3.24 | 3.24 |
| 369.86 | 3.38 | 3.38 |
| 294.36 | 2.77 | 2.77 |
| 330.82 | 3.34 | 3.34 |
| 313.79 | 3.72 | 3.72 |
| 302.77 | 3.07 | 3.07 |