Basic Information
ID: ALA5043746
Type: Binding
Description: Inhibition of recombinant human SGK1 expressed in baculovirus expression system using 5-carboxyfluorescein -RPRAATF-NH2 as substrate preincubated for 30 mins followed by substrate addition in presence of 500 uM ATP and measured after 60 mins by microfluidics assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5043746
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.30 | 3.71 | 3.71 |
| 517.97 | 4.30 | 4.30 |
| 430.88 | 3.06 | 3.06 |
| 534.98 | 4.00 | 4.00 |
| 531.43 | 3.78 | 3.78 |
| 531.43 | 3.78 | 3.78 |
| 532.99 | 3.29 | 3.29 |
| 559.48 | 4.41 | 4.41 |
| 532.99 | 3.28 | 3.28 |
| 573.51 | 4.95 | 4.95 |
| 532.99 | 3.78 | 3.78 |
| 543.40 | 3.78 | 3.78 |
| 462.32 | 3.83 | 3.83 |
| 505.39 | 3.42 | 3.42 |
| 545.04 | 4.78 | 4.78 |
| 573.09 | 5.61 | 5.61 |
| 531.43 | 3.82 | 3.82 |
| 490.37 | 4.48 | 4.48 |
| 476.35 | 4.09 | 4.09 |
| 599.01 | 5.33 | 5.33 |
| 542.41 | 4.39 | 4.39 |
| 532.00 | 4.60 | 4.60 |
| 571.49 | 4.70 | 4.70 |
| 520.40 | 3.80 | 3.80 |
| 543.39 | 4.65 | 4.65 |
| 587.12 | 5.95 | 5.95 |
| 525.95 | 4.69 | 4.69 |
| 516.99 | 4.05 | 4.05 |
| 425.86 | 2.93 | 2.93 |
| 545.04 | 4.78 | 4.78 |
| 547.47 | 4.41 | 4.41 |
| 556.44 | 4.43 | 4.43 |
| 529.98 | 4.81 | 4.81 |
| 575.07 | 4.41 | 4.41 |
| 516.99 | 4.05 | 4.05 |
| 526.94 | 4.81 | 4.81 |
| 545.45 | 4.17 | 4.17 |
| 504.40 | 4.87 | 4.87 |
| 517.97 | 4.48 | 4.48 |
| 552.97 | 4.30 | 4.30 |
| 526.93 | 3.89 | 3.89 |
| 490.95 | 3.65 | 3.65 |
| 557.42 | 3.75 | 3.75 |
| 560.45 | 4.51 | 4.51 |
| 545.04 | 4.64 | 4.64 |
| 585.52 | 4.95 | 4.95 |
| 521.96 | 2.90 | 2.90 |
| 573.51 | 4.80 | 4.80 |
| 461.91 | 4.32 | 4.32 |
| 557.05 | 4.93 | 4.93 |
| 575.48 | 3.53 | 3.53 |
| 491.93 | 3.68 | 3.68 |
| 542.41 | 4.39 | 4.39 |
| 574.48 | 4.70 | 4.70 |
| 544.38 | 3.18 | 3.18 |
| 559.07 | 5.17 | 5.17 |