Basic Information
ID: ALA5044131
Type: ADME
Description: Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis
Format: BAO_0000219
Organism: Sus scrofa
Cell type: LLC-PK1
Target: ADMET(ALA612558)
Document: ALA5042510
Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in rat Mdr1a-transfected pig LLC-PK1 cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5044131
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.35 | 4.98 | 4.98 |
| 491.42 | 4.23 | 4.23 |
| 375.44 | 3.62 | 3.62 |
| 504.97 | 4.05 | 4.05 |
| 543.38 | 4.34 | 4.34 |
| 408.46 | 3.57 | 3.57 |
| 545.37 | 5.32 | 5.32 |
| 501.34 | 4.67 | 4.67 |
| 477.37 | 4.74 | 4.74 |
| 460.37 | 3.73 | 3.73 |
| 400.49 | 4.18 | 4.18 |
| 420.90 | 4.52 | 4.52 |
| 438.96 | 4.44 | 4.44 |
| 349.44 | 4.11 | 4.11 |
| 459.38 | 4.79 | 4.79 |
| 374.45 | 3.79 | 3.79 |