Basic Information
ID: ALA5044151
Type: ADME
Description: Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral side in mouse Bcrp-transfected dog MDCK-II cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-II
Target: ADMET(ALA612558)
Document: ALA5042510
Efflux ratio of apparent permeability across basolateral to apical over apical to basolateral side in mouse Bcrp-transfected dog MDCK-II cells at 0.1 to 1 uM measured after 3 hrs by LC/MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5044151
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.42 | 4.23 | 4.23 |
| 504.97 | 4.05 | 4.05 |
| 543.38 | 4.34 | 4.34 |
| 477.37 | 4.74 | 4.74 |
| 438.96 | 4.44 | 4.44 |
| 459.38 | 4.79 | 4.79 |