Basic Information
ID: ALA5044165
Type: Binding
Description: Ex vivo inhibition of LRRK2 in human PBMC assessed as unbound concentration required for reduction in LRRK2 phosphorylation at Ser935 residue incubated for 90 mins by MSD assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PBMC
Target: Leucine-rich repeat serine/threonine-protein kinase 2(ALA1075104)
Document: ALA5042510
Ex vivo inhibition of LRRK2 in human PBMC assessed as unbound concentration required for reduction in LRRK2 phosphorylation at Ser935 residue incubated for 90 mins by MSD assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5044165
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.97 | 4.05 | 4.05 |
| 543.38 | 4.34 | 4.34 |
| 457.29 | 4.87 | 4.87 |