Basic Information
ID: ALA5044220
Type: ADME
Description: Drug metabolism in rat assessed as AUC of (3R,4R)-4((3S,4S)-4-(6-Chloro-2-((5-chloro-1((R)-2,2-difluorocyclopropyl-1H-pyrazol-4-yl)amino)quinazolin-7-yl)-3-fluoropiperidin-1-yl)tetrahydrofuran-3-ol metabolite by LC-MS/MS analysis relative to parent compound
Format: BAO_0000019
Organism: Rattus norvegicus
Target: ADMET(ALA612558)
Document: ALA5042510
Drug metabolism in rat assessed as AUC of (3R,4R)-4((3S,4S)-4-(6-Chloro-2-((5-chloro-1((R)-2,2-difluorocyclopropyl-1H-pyrazol-4-yl)amino)quinazolin-7-yl)-3-fluoropiperidin-1-yl)tetrahydrofuran-3-ol metabolite by LC-MS/MS analysis relative to parent compound: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5044220
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.97 | 4.05 | 4.05 |
| 543.38 | 4.34 | 4.34 |