Assay Report Card

Basic Information

ID: ALA5044220

Type: ADME

Description: Drug metabolism in rat assessed as AUC of (3R,4R)-4((3S,4S)-4-(6-Chloro-2-((5-chloro-1((R)-2,2-difluorocyclopropyl-1H-pyrazol-4-yl)amino)quinazolin-7-yl)-3-fluoropiperidin-1-yl)tetrahydrofuran-3-ol metabolite by LC-MS/MS analysis relative to parent compound

Organism: Rattus norvegicus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
504.974.054.05
543.384.344.34