Basic Information
ID: ALA5045601
Type: Binding
Description: Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy 6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate addition and measured after 30 mins by BD FACSCalibur flow cytometry analysis
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5045601
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 501.55 | 7.63 | 7.63 |
| 487.52 | 7.36 | 7.36 |
| 517.55 | 6.85 | 6.85 |
| 501.55 | 7.75 | 7.75 |
| 607.67 | 8.62 | 8.62 |
| 529.56 | 7.62 | 7.62 |
| 501.50 | 6.88 | 6.88 |
| 519.52 | 6.80 | 6.80 |
| 487.52 | 7.14 | 7.14 |
| 505.54 | 6.70 | 6.70 |
| 489.54 | 7.60 | 7.60 |
| 499.53 | 7.80 | 7.80 |
| 501.55 | 7.89 | 7.89 |
| 517.55 | 6.71 | 6.71 |
| 519.52 | 6.80 | 6.80 |
| 501.50 | 6.88 | 6.88 |
| 531.57 | 7.36 | 7.36 |
| 487.52 | 7.36 | 7.36 |
| 487.52 | 7.36 | 7.36 |
| 501.50 | 6.88 | 6.88 |
| 559.58 | 8.23 | 8.23 |
| 505.54 | 6.70 | 6.70 |
| 501.50 | 6.88 | 6.88 |
| 517.55 | 6.99 | 6.99 |
| 499.53 | 7.66 | 7.66 |
| 580.44 | 8.39 | 8.39 |
| 505.54 | 6.70 | 6.70 |
| 487.52 | 7.36 | 7.36 |
| 519.52 | 6.80 | 6.80 |
| 489.54 | 7.75 | 7.75 |
| 519.52 | 6.80 | 6.80 |
| 487.52 | 7.36 | 7.36 |
| 523.50 | 7.39 | 7.39 |
| 564.62 | 7.82 | 7.82 |
| 487.52 | 7.36 | 7.36 |
| 501.55 | 7.60 | 7.60 |
| 517.55 | 6.85 | 6.85 |
| 529.56 | 7.62 | 7.62 |
| 505.54 | 6.70 | 6.70 |
| 461.48 | 6.97 | 6.97 |