Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4...

Basic Information

ID: ALA5045601

Type: Binding

Description: Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy 6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate addition and measured after 30 mins by BD FACSCalibur flow cytometry analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target:  Purinergic receptor P2Y14(ALA4518)

Document:  ALA5042543

Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy 6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate addition and measured after 30 mins by BD FACSCalibur flow cytometry analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
501.557.637.63
487.527.367.36
517.556.856.85
501.557.757.75
607.678.628.62
529.567.627.62
501.506.886.88
519.526.806.80
487.527.147.14
505.546.706.70
489.547.607.60
499.537.807.80
501.557.897.89
517.556.716.71
519.526.806.80
501.506.886.88
531.577.367.36
487.527.367.36
487.527.367.36
501.506.886.88
559.588.238.23
505.546.706.70
501.506.886.88
517.556.996.99
499.537.667.66
580.448.398.39
505.546.706.70
487.527.367.36
519.526.806.80
489.547.757.75
519.526.806.80
487.527.367.36
523.507.397.39
564.627.827.82
487.527.367.36
501.557.607.60
517.556.856.85
529.567.627.62
505.546.706.70
461.486.976.97