Basic Information
ID: ALA5045987
Type: Binding
Description: Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 to 10 uM incubated for 24 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: VHL/Histone deacetylase 1(ALA4630745)
Document: ALA5042553
Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as induction of HDAC1 degradation at 1 to 10 uM incubated for 24 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5045987
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 939.19 | 6.73 | 6.73 |
| 888.06 | 3.77 | 3.77 |
| 810.03 | 6.43 | 6.43 |
| 934.24 | 9.33 | 9.33 |
| 880.17 | 8.38 | 8.38 |
| 880.13 | 4.88 | 4.88 |
| 897.11 | 5.56 | 5.56 |
| 838.09 | 7.21 | 7.21 |
| 926.13 | 5.48 | 5.48 |
| 892.16 | 8.16 | 8.16 |
| 799.95 | 3.73 | 3.73 |
| 824.06 | 6.82 | 6.82 |
| 844.00 | 3.75 | 3.75 |