Assay Report Card

Basic Information

ID: ALA5045989

Type: Binding

Description: Protac activity at VHL/HDAC3 in human HCT-116 cells assessed as induction of HDAC3 degradation at 1 to 10 uM incubated for 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
888.063.773.77
810.036.436.43
936.238.788.78
880.134.884.88
838.097.217.21
799.953.733.73
870.117.747.74
824.066.826.82
844.003.753.75