Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 48 hrs by Western blot analysis

Basic Information

ID: ALA5046029

Type: Binding

Description: Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 48 hrs by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HCT-116

Target: VHL/Histone deacetylase 1(ALA4630745)

Document: ALA5042553

Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 48 hrs by Western blot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5046029

Activity

Total(3)

Parent Molecular Weight	ALogP	Polar Surface Area
269.30	2.48	2.48
840.06	6.06	6.06
856.06	5.29	5.29

Parent Molecular Weight

ALogP

Polar Surface Area

269.30

2.48

840.06

6.06

856.06

5.29

Protac activity at VHL/HDAC1 in human HCT-116 cells assessed as reduction in SIN3A level at 10 uM measured after 48 hrs by Western blot analysis

Basic Information

Activity Charts

Compound Summary