Basic Information
ID: ALA5046504
Type: Functional
Description: Neuroprotective activity against MPTP/probenedcic-induced DAergic neuron loss in C57BL/6 mouse model of Parkinson's disease assessed as increase in GDNF level in SNpc at 1 to 2 mg/kg, ig pretreated with MPTP/probenecid for 32 days followed by compound addition for next 20 days and measured after 20 days by immunofluorescence analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6
Target: Mus musculus(ALA375)
Document: ALA5046219
Neuroprotective activity against MPTP/probenedcic-induced DAergic neuron loss in C57BL/6 mouse model of Parkinson's disease assessed as increase in GDNF level in SNpc at 1 to 2 mg/kg, ig pretreated with MPTP/probenecid for 32 days followed by compound addition for next 20 days and measured after 20 days by immunofluorescence analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5046504
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.35 | 3.76 | 3.76 |