Basic Information
ID: ALA5046937
Type: Functional
Description: Effect of PI3K signalling pathway in JAK2V6175 transgenic myelofibrosis C57BL/6 mouse spleen assessed as reduction in ERK1/2 phosphorylation at 325 mg/kg, po administered daily for 5 days by flow cytometry analysis
Organism: Mus musculus
Strain: C57BL/6
Tissue: Spleen
Activity Charts
Bioactivity
Activity Types for Assay ALA5046937
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 913.64 | 5.57 | 5.57 |
| 957.70 | 4.96 | 4.96 |