Basic Information
ID: ALA5047426
Type: Binding
Description: Inhibition of GST-fused human JAK1 (854 to 1154 residues) expressed in insect cells using ULight-JAK-1 Tyr1023 peptide as substrate preincubated for 30 mins followed by substrate addition and further incubated for 20 mins in presence of ATP by FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5047426
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 324.39 | 2.24 | 2.24 |
| 255.28 | 2.12 | 2.12 |
| 356.40 | 3.08 | 3.08 |
| 364.45 | 2.91 | 2.91 |
| 409.51 | 4.04 | 4.04 |
| 469.61 | 4.64 | 4.64 |
| 366.43 | 2.50 | 2.50 |
| 407.49 | 3.98 | 3.98 |
| 355.42 | 2.92 | 2.92 |
| 441.55 | 3.86 | 3.86 |
| 407.49 | 3.98 | 3.98 |
| 323.40 | 2.27 | 2.27 |
| 372.40 | 2.37 | 2.37 |
| 395.48 | 3.79 | 3.79 |
| 313.33 | 3.29 | 3.29 |
| 356.40 | 3.08 | 3.08 |
| 356.40 | 3.08 | 3.08 |
| 356.40 | 3.08 | 3.08 |
| 322.42 | 2.65 | 2.65 |
| 342.37 | 2.69 | 2.69 |
| 356.40 | 3.08 | 3.08 |
| 423.49 | 3.71 | 3.71 |
| 365.44 | 2.53 | 2.53 |
| 347.38 | 3.49 | 3.49 |
| 356.40 | 2.71 | 2.71 |
| 372.40 | 2.05 | 2.05 |
| 395.48 | 3.79 | 3.79 |
| 395.48 | 3.79 | 3.79 |
| 267.29 | 2.59 | 2.59 |
| 313.33 | 3.29 | 3.29 |
| 471.58 | 3.49 | 3.49 |