Basic Information
ID: ALA5047434
Type: Binding
Description: Inhibition of JAK1/JAK3 signalling in human PBMC assessed as inhibition of IL-2 stimulated IFN-gamma release incubated for 1 hr followed by IL-2 stimulation by MSD assay
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA5047434
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.40 | 3.08 | 3.08 |
| 409.51 | 4.04 | 4.04 |
| 469.61 | 4.64 | 4.64 |
| 407.49 | 3.98 | 3.98 |
| 355.42 | 2.92 | 2.92 |
| 441.55 | 3.86 | 3.86 |
| 407.49 | 3.98 | 3.98 |
| 395.48 | 3.79 | 3.79 |
| 313.33 | 3.29 | 3.29 |
| 356.40 | 3.08 | 3.08 |
| 356.40 | 3.08 | 3.08 |
| 356.40 | 3.08 | 3.08 |
| 342.37 | 2.69 | 2.69 |
| 356.40 | 3.08 | 3.08 |
| 423.49 | 3.71 | 3.71 |
| 356.40 | 2.71 | 2.71 |
| 372.40 | 2.05 | 2.05 |
| 395.48 | 3.79 | 3.79 |
| 395.48 | 3.79 | 3.79 |
| 471.58 | 3.49 | 3.49 |