Basic Information
ID: ALA5048089
Type: Functional
Description: Antitumor activity against MTAP/CDKN2A deleted human Lu-99 cells xenografted in Hsd athymic nude mouse assessed as reduction in PRMT5 mediated SDMA level in tumor at 12.5 to 100 mg/kg, po qd administered via oral gavage for 21 days relative to control
Format: BAO_0000218
Organism: Mus musculus
Cell type: Lu-99 cell line
Target: Lu-99 cell line(ALA614651)
Document: ALA5046262
Antitumor activity against MTAP/CDKN2A deleted human Lu-99 cells xenografted in Hsd athymic nude mouse assessed as reduction in PRMT5 mediated SDMA level in tumor at 12.5 to 100 mg/kg, po qd administered via oral gavage for 21 days relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5048089
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.89 | 3.65 | 3.65 |