Basic Information
ID: ALA5048363
Type: Binding
Description: Inhibition of recombinant human N- terminal His-tagged /TEV cleavage site fused GGPPS (1 to 300 residues) expressed in Escherichia coli BL21 (DE3) using FPP and IPP as substrates preincubated for 10 mins followed by substrate addition measured after 6 mins by by beckman coulter counting method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5048363
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.28 | 2.41 | 2.41 |
| 520.40 | 3.66 | 3.66 |
| 520.40 | 3.66 | 3.66 |
| 538.39 | 3.80 | 3.80 |
| 568.42 | 3.81 | 3.81 |
| 552.42 | 4.11 | 4.11 |
| 534.43 | 3.59 | 3.59 |
| 592.51 | 4.51 | 4.51 |
| 552.42 | 4.11 | 4.11 |
| 583.43 | 4.20 | 4.20 |
| 604.47 | 3.36 | 3.36 |
| 564.45 | 3.74 | 3.74 |
| 640.52 | 4.66 | 4.66 |
| 564.45 | 3.74 | 3.74 |
| 604.47 | 3.36 | 3.36 |
| 535.42 | 2.99 | 2.99 |
| 588.47 | 3.66 | 3.66 |
| 613.32 | 4.73 | 4.73 |
| 589.39 | 4.08 | 4.08 |
| 640.52 | 4.66 | 4.66 |
| 568.42 | 3.81 | 3.81 |
| 592.51 | 4.51 | 4.51 |
| 629.32 | 4.43 | 4.43 |
| 553.41 | 4.19 | 4.19 |
| 588.40 | 4.68 | 4.68 |