Basic Information
ID: ALA5048610
Type: Binding
Description: Protac activity at VHL/AKT in human BT-474 cells assessed as inhibition of downstream signalling by measuring reduction in PRAS40 phosphorylation at T246 residue at 1 uM measured after 24 hrs Western blot analysis
Organism: Homo sapiens
Cell type: BT-474
Activity Charts
Bioactivity
Activity Types for Assay ALA5048610
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.92 | 2.10 | 2.10 |
| 430.57 | 2.07 | 2.07 |