Basic Information
ID: ALA5048796
Type: ADME
Description: Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5048796
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.54 | 3.21 | 3.21 |
| 363.51 | 2.39 | 2.39 |
| 365.53 | 2.61 | 2.61 |
| 365.53 | 2.61 | 2.61 |
| 463.67 | 3.76 | 3.76 |
| 483.65 | 4.82 | 4.82 |
| 406.53 | 2.10 | 2.10 |
| 408.55 | 2.32 | 2.32 |
| 308.43 | 2.50 | 2.50 |
| 365.53 | 2.61 | 2.61 |
| 421.63 | 3.99 | 3.99 |
| 419.62 | 3.65 | 3.65 |
| 435.62 | 2.98 | 2.98 |
| 393.58 | 3.21 | 3.21 |
| 421.59 | 2.64 | 2.64 |
| 366.51 | 2.00 | 2.00 |
| 366.51 | 2.00 | 2.00 |
| 449.64 | 3.42 | 3.42 |
| 413.57 | 3.53 | 3.53 |
| 365.53 | 2.61 | 2.61 |
| 308.43 | 2.50 | 2.50 |
| 406.53 | 2.10 | 2.10 |
| 363.51 | 2.39 | 2.39 |
| 477.65 | 2.75 | 2.75 |
| 497.68 | 5.16 | 5.16 |