Basic Information
ID: ALA5049087
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate at 10 uM in presence of NADPH generating system incubated for 10 mins
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA5049087
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.43 | 5.22 | 5.22 |
| 447.41 | 3.65 | 3.65 |