Basic Information
ID: ALA5050105
Type: Binding
Description: PROTAC activity at CRBN/JAK2 in human MHHCALL4 cells assessed as protein degradation at 100 nM measured after 24 hrs by immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MHHCALL4
Target: Cereblon/Tyrosine-protein kinase JAK2(ALA4742263)
Document: ALA5046306
PROTAC activity at CRBN/JAK2 in human MHHCALL4 cells assessed as protein degradation at 100 nM measured after 24 hrs by immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5050105
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 832.90 | 2.86 | 2.86 |
| 873.96 | 1.79 | 1.79 |
| 764.87 | 3.95 | 3.95 |
| 887.08 | 4.86 | 4.86 |
| 830.98 | 3.44 | 3.44 |
| 804.94 | 2.91 | 2.91 |
| 764.87 | 3.95 | 3.95 |
| 763.88 | 3.98 | 3.98 |
| 818.96 | 3.30 | 3.30 |
| 833.89 | 2.83 | 2.83 |
| 844.91 | 2.64 | 2.64 |
| 775.90 | 3.76 | 3.76 |