Basic Information
ID: ALA5050122
Type: Binding
Description: PROTAC activity at CRBN/JAK2 in human CD45(+/+) leukemia cell derived from PDX-SJBALL020589 assessed as protein degradation measured after 24 hrs by immunoblot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CD45(+/+) leukemic cell
Target: Cereblon/Tyrosine-protein kinase JAK2(ALA4742263)
Document: ALA5046306
PROTAC activity at CRBN/JAK2 in human CD45(+/+) leukemia cell derived from PDX-SJBALL020589 assessed as protein degradation measured after 24 hrs by immunoblot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5050122
DC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 818.96 | 3.30 | 3.30 |