Basic Information
ID: ALA5050624
Type: Binding
Description: Inhibition of IDH1 R132H mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-KG as substrate incubated for 60 mins by Kinase-GLO reagent based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5050624
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.65 | 5.33 | 5.33 |
| 462.59 | 4.63 | 4.63 |
| 554.71 | 4.43 | 4.43 |
| 450.58 | 4.94 | 4.94 |
| 494.61 | 5.16 | 5.16 |
| 511.07 | 5.68 | 5.68 |
| 478.59 | 4.01 | 4.01 |
| 452.56 | 4.14 | 4.14 |
| 529.61 | 5.09 | 5.09 |
| 490.65 | 5.27 | 5.27 |
| 476.62 | 5.19 | 5.19 |
| 454.57 | 4.70 | 4.70 |
| 453.59 | 4.28 | 4.28 |
| 505.52 | 4.06 | 4.06 |
| 463.58 | 4.03 | 4.03 |
| 476.62 | 5.02 | 5.02 |
| 494.61 | 5.16 | 5.16 |
| 450.58 | 4.49 | 4.49 |
| 453.54 | 3.73 | 3.73 |
| 496.58 | 4.15 | 4.15 |
| 494.61 | 5.16 | 5.16 |
| 471.53 | 3.87 | 3.87 |
| 471.53 | 3.87 | 3.87 |
| 465.53 | 4.18 | 4.18 |
| 463.58 | 4.03 | 4.03 |