ID: ALA5050627
Type: ADME
Description: Drug metabolism in rat liver microsomes assessed as GSH-adduct formation at 1 mg/ml and measured after 60 mins in presence of glutathione and NADPH by ion chromatogram analysis relative to control
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Bioactivity
Activity Types for Assay ALA5050627
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
490.65 | 5.33 | 5.33 |
462.59 | 4.63 | 4.63 |
554.71 | 4.43 | 4.43 |
450.58 | 4.94 | 4.94 |
494.61 | 5.16 | 5.16 |
511.07 | 5.68 | 5.68 |
478.59 | 4.01 | 4.01 |
452.56 | 4.14 | 4.14 |
529.61 | 5.09 | 5.09 |
490.65 | 5.27 | 5.27 |
476.62 | 5.19 | 5.19 |
453.59 | 4.28 | 4.28 |
505.52 | 4.06 | 4.06 |
463.58 | 4.03 | 4.03 |
476.62 | 5.02 | 5.02 |
494.61 | 5.16 | 5.16 |
450.58 | 4.49 | 4.49 |
453.54 | 3.73 | 3.73 |
496.58 | 4.15 | 4.15 |
494.61 | 5.16 | 5.16 |
471.53 | 3.87 | 3.87 |
471.53 | 3.87 | 3.87 |
465.53 | 4.18 | 4.18 |
463.58 | 4.03 | 4.03 |