Basic Information
ID: ALA5050632
Type: ADME
Description: Substrate activity at P-gp (unknown origin) transfected in LLC-PK1 cells expressing human MDR1 gene assessed as efflux ratio of permeability across basolateral to apical membrane at 0.1 uM
Organism: Homo sapiens
Cell type: LLC-PK1
Activity Charts
Bioactivity
Activity Types for Assay ALA5050632
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 490.65 | 5.33 | 5.33 |
| 462.59 | 4.63 | 4.63 |
| 554.71 | 4.43 | 4.43 |
| 450.58 | 4.94 | 4.94 |
| 494.61 | 5.16 | 5.16 |
| 452.56 | 4.14 | 4.14 |
| 476.62 | 5.19 | 5.19 |
| 454.57 | 4.70 | 4.70 |
| 453.59 | 4.28 | 4.28 |
| 505.52 | 4.06 | 4.06 |
| 463.58 | 4.03 | 4.03 |
| 476.62 | 5.02 | 5.02 |
| 494.61 | 5.16 | 5.16 |
| 453.54 | 3.73 | 3.73 |
| 496.58 | 4.15 | 4.15 |
| 494.61 | 5.16 | 5.16 |
| 471.53 | 3.87 | 3.87 |
| 471.53 | 3.87 | 3.87 |
| 465.53 | 4.18 | 4.18 |
| 463.58 | 4.03 | 4.03 |