Basic Information
ID: ALA5050872
Type: Binding
Description: Inhibition of ATF6 activity in human U2OS cells at 1 uM in presence of ER stress inducer thapsigargin (Tg) measured by TRE-luciferase reporter assay relative to control
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA5050872
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.38 | 5.83 | 5.83 |
| 510.39 | 5.88 | 5.88 |
| 509.41 | 6.14 | 6.14 |
| 511.45 | 6.30 | 6.30 |
| 484.36 | 5.78 | 5.78 |
| 470.33 | 5.47 | 5.47 |
| 484.36 | 6.03 | 6.03 |
| 505.42 | 6.24 | 6.24 |
| 497.42 | 5.74 | 5.74 |
| 511.45 | 6.30 | 6.30 |
| 443.35 | 5.52 | 5.52 |
| 509.41 | 6.14 | 6.14 |
| 495.38 | 5.83 | 5.83 |
| 516.35 | 6.15 | 6.15 |
| 509.41 | 6.14 | 6.14 |
| 525.48 | 6.61 | 6.61 |
| 470.33 | 5.47 | 5.47 |
| 361.36 | 3.31 | 3.31 |
| 524.42 | 6.45 | 6.45 |
| 484.36 | 6.03 | 6.03 |
| 445.38 | 4.95 | 4.95 |
| 495.38 | 5.83 | 5.83 |
| 360.37 | 3.92 | 3.92 |
| 402.33 | 4.45 | 4.45 |
| 470.33 | 5.47 | 5.47 |
| 513.43 | 5.09 | 5.09 |
| 526.47 | 6.00 | 6.00 |
| 482.34 | 4.67 | 4.67 |
| 334.34 | 3.43 | 3.43 |
| 443.35 | 5.77 | 5.77 |
| 360.37 | 3.92 | 3.92 |
| 443.35 | 5.52 | 5.52 |
| 499.35 | 5.41 | 5.41 |
| 495.38 | 5.30 | 5.30 |
| 501.41 | 5.89 | 5.89 |
| 458.39 | 4.53 | 4.53 |
| 460.38 | 5.51 | 5.51 |
| 500.42 | 6.50 | 6.50 |
| 509.41 | 6.14 | 6.14 |
| 481.36 | 5.52 | 5.52 |
| 442.34 | 4.50 | 4.50 |
| 481.36 | 5.27 | 5.27 |
| 495.38 | 5.83 | 5.83 |
| 508.40 | 6.42 | 6.42 |
| 495.38 | 5.58 | 5.58 |
| 509.41 | 6.14 | 6.14 |
| 529.83 | 6.49 | 6.49 |
| 513.43 | 5.09 | 5.09 |
| 505.42 | 6.24 | 6.24 |
| 443.35 | 5.77 | 5.77 |
| 484.36 | 6.03 | 6.03 |
| 508.43 | 5.58 | 5.58 |
| 429.32 | 5.21 | 5.21 |
| 371.40 | 3.72 | 3.72 |
| 445.38 | 4.95 | 4.95 |
| 429.32 | 4.57 | 4.57 |
| 494.40 | 5.57 | 5.57 |
| 403.23 | 4.74 | 4.74 |
| 496.37 | 5.23 | 5.23 |
| 495.38 | 5.83 | 5.83 |
| 491.40 | 5.68 | 5.68 |
| 521.42 | 6.22 | 6.22 |
| 427.34 | 4.32 | 4.32 |
| 513.43 | 5.09 | 5.09 |
| 494.40 | 5.57 | 5.57 |
| 496.37 | 5.23 | 5.23 |
| 496.37 | 5.23 | 5.23 |
| 501.41 | 5.89 | 5.89 |
| 445.38 | 4.95 | 4.95 |
| 495.38 | 5.83 | 5.83 |
| 495.38 | 5.83 | 5.83 |
| 404.27 | 4.21 | 4.21 |
| 529.83 | 6.49 | 6.49 |
| 420.28 | 4.60 | 4.60 |
| 509.41 | 6.14 | 6.14 |
| 466.37 | 5.56 | 5.56 |
| 525.48 | 6.61 | 6.61 |
| 484.36 | 5.78 | 5.78 |
| 511.45 | 6.30 | 6.30 |
| 462.43 | 4.82 | 4.82 |
| 359.35 | 3.30 | 3.30 |
| 484.36 | 5.78 | 5.78 |
| 481.36 | 5.27 | 5.27 |
| 470.33 | 5.72 | 5.72 |
| 431.31 | 4.40 | 4.40 |
| 495.38 | 5.83 | 5.83 |
| 419.29 | 5.21 | 5.21 |
| 454.37 | 5.58 | 5.58 |
| 496.37 | 5.23 | 5.23 |
| 512.44 | 5.82 | 5.82 |
| 482.34 | 4.67 | 4.67 |
| 495.39 | 4.76 | 4.76 |
| 509.41 | 6.14 | 6.14 |
| 526.47 | 6.00 | 6.00 |
| 428.34 | 5.18 | 5.18 |
| 428.34 | 5.18 | 5.18 |
| 429.32 | 4.57 | 4.57 |
| 509.41 | 6.14 | 6.14 |
| 495.38 | 5.83 | 5.83 |
| 495.38 | 5.58 | 5.58 |
| 445.38 | 4.95 | 4.95 |
| 508.43 | 5.58 | 5.58 |
| 529.83 | 6.49 | 6.49 |
| 512.44 | 5.70 | 5.70 |
| 495.39 | 4.76 | 4.76 |
| 496.37 | 5.23 | 5.23 |
| 495.38 | 5.83 | 5.83 |
| 526.47 | 6.00 | 6.00 |
| 511.45 | 6.30 | 6.30 |
| 496.37 | 5.23 | 5.23 |
| 482.34 | 4.67 | 4.67 |
| 490.41 | 6.28 | 6.28 |
| 495.38 | 5.58 | 5.58 |
| 486.40 | 5.94 | 5.94 |
| 509.41 | 6.14 | 6.14 |
| 505.45 | 6.32 | 6.32 |
| 414.25 | 4.54 | 4.54 |
| 360.37 | 3.72 | 3.72 |
| 429.32 | 5.46 | 5.46 |
| 500.42 | 6.50 | 6.50 |
| 513.43 | 5.09 | 5.09 |
| 360.37 | 3.92 | 3.92 |
| 512.44 | 5.70 | 5.70 |
| 515.80 | 5.92 | 5.92 |
| 524.42 | 6.45 | 6.45 |
| 513.43 | 5.09 | 5.09 |